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. 2015 Apr;105(4):e34-45.
doi: 10.2105/AJPH.2014.302469. Epub 2015 Feb 25.

Systematic review of racial disparities in human papillomavirus-associated anal dysplasia and anal cancer among men who have sex with men

Tim Walsh  1 , Clara Bertozzi-Villa, John A Schneider
Affiliations

Systematic review of racial disparities in human papillomavirus-associated anal dysplasia and anal cancer among men who have sex with men

Tim Walsh et al. Am J Public Health. 2015 Apr.

Abstract

We systematically reviewed the literature on anal human papillomavirus (HPV) infection, dysplasia, and cancer among Black and White men who have sex with men (MSM) to determine if a racial disparity exists. We searched 4 databases for articles up to March 2014. Studies involving Black MSM are nearly absent from the literature. Of 25 eligible studies, 2 stratified by race and sexual behavior. Both reported an elevated rate of abnormal anal outcomes among Black MSM. White MSM had a 1.3 times lower prevalence of group-2 HPV (P < .01) and nearly 13% lower prevalence of anal dysplasia than did Black MSM. We were unable to determine factors driving the absence of Black MSM in this research and whether disparities in clinical care exist. Elevated rates of abnormal anal cytology among Black MSM in 2 studies indicate a need for future research in this population.

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Figures

FIGURE 1—
FIGURE 1—
Study eligibility criteria used for analyzing anal human papillomavirus, dysplasia, and cancer (HDC) disparity for systematic review of literature up to March 2014: United States. Note. MSM = men who have sex with men.
See this image and copyright information in PMC

References

    1. Silverberg MJ, Lau B, Justice AC et al. Risk of anal cancer in HIV-infected and HIV-uninfected individuals in North America. Clin Infect Dis. 2012;54(7):1026–1034. - PMC - PubMed
    1. Machalek DA, Grulich AE, Jin F, Templeton DJ, Poynten IM. The epidemiology and natural history of anal human papillomavirus infection in men who have sex with men. Sex Health. 2012;9(6):527–537. - PubMed
    1. Bouvard V, Baan R, Straif K et al. A review of human carcinogens—Part B: biological agents. Lancet Oncol. 2009;10(4):321–322. - PubMed
    1. Veldhuijzen NJ, Snijders PJ, Reiss P, Meijer CJ, van de Wijgert JH. Factors affecting transmission of mucosal human papillomavirus. Lancet Infect Dis. 2010;10(12):862–874. - PubMed
    1. Niccolai LM, Russ C, Julian PJ et al. Individual and geographic disparities in human papillomavirus types 16/18 in high-grade cervical lesions: associations with race, ethnicity, and poverty. Cancer. 2013;119(16):3052–3058. - PubMed

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