Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2015 Feb 26;372(9):796-7.
doi: 10.1056/NEJMp1414786.

Anesthetic neurotoxicity--clinical implications of animal models

Bob A Rappaport  1 , Santhanam Suresh, Sharon Hertz, Alex S Evers, Beverley A Orser
Affiliations

Anesthetic neurotoxicity--clinical implications of animal models

Bob A Rappaport et al. N Engl J Med. .

Abstract

Some anesthetics and sedatives have been shown to cause neurotoxic effects in laboratory animals. The FDA collaboration SmartTots recommends undertaking large-scale clinical studies and avoiding nonurgent surgical procedures requiring anesthesia in children younger than 3 years of age.

PubMed Disclaimer