Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2015:159:A8054.

[Ceftriaxone-induced immune haemolytic anaemia and multi-organ failure]

[Article in Dutch]
Chantal E Mulkens  1 , Ellen G van Lochem, Claudia C Folman, Ellen van der Spek, Henk J van Leeuwen
Affiliations
  • PMID: 25714764
Case Reports

[Ceftriaxone-induced immune haemolytic anaemia and multi-organ failure]

[Article in Dutch]
Chantal E Mulkens et al. Ned Tijdschr Geneeskd. 2015.

Abstract

Background: Drug-induced immune haemolytic anaemia (DIIHA) is caused by various drugs or their metabolites. Cephalosporins are associated with haemolytic anaemia but multi-organ failure is rarely described.

Case description: We report the case of a 57-year-old female who was diagnosed with neuroborreliosis and treated with ceftriaxone. The patient developed severe DIIHA. Massive intravascular haemolysis led to shock and acute renal failure, necessitating mechanical ventilation and dialysis. Treatment with ceftriaxone was discontinued and glucocorticoids were prescribed. The patient recovered slowly but fully.

Conclusion: Ceftriaxone-induced immune haemolytic anaemia is a rare but potentially fatal condition.

PubMed Disclaimer

Publication types

MeSH terms