The Prevalence of Posttraumatic Stress Disorder Symptoms among Addiction Treatment Patients with Cocaine Use Disorders
- PMID: 25715071
- PMCID: PMC4876862
- DOI: 10.1080/02791072.2014.977501
The Prevalence of Posttraumatic Stress Disorder Symptoms among Addiction Treatment Patients with Cocaine Use Disorders
Abstract
Co-occurring cocaine use and posttraumatic stress disorders are prevalent and associated with negative treatment, health and societal consequences. This study examined the relationships among PTSD symptoms, gender, and cocaine use problems. Within a cross-sectional design, we gathered archival point prevalence data on new admissions (n = 573) to three addiction treatment agencies. Demographic, substance use, and PTSD symptom information were collected across the three agencies. Logistic regression analyses revealed that patients with cocaine use disorders had a two-fold increased odds for a probable PTSD diagnosis, compared to patients without a cocaine use disorder (OR = 2.19, 95% CI = 1.49-3.22, p < 0.001). Among females with cocaine use disorder, multinomial regression yielded a significant increase in the risk of moderate (RRR = 2.12, 95% CI = 1.10-4.10, p < 0.05) and severe (RRR = 2.87, 95% CI = 1.33-6.21, p < 0.01) PTSD symptoms. Males with cocaine use disorders had a two-fold increase in the risk of moderate PTSD symptoms (RRR = 2.13, 95% CI = 1.23-3.68, p < 0.01), but had no increased risk of developing severe PTSD symptoms (RRR = 1.93, 95% CI = 0.85-4.39, p = 0.117). Cocaine use appears to impact the risk of PTSD symptoms, especially in females. Future research should explore the generalizability of these findings to more racially and ethnically diverse samples, as well as among persons with this comorbidity who are not engaged in treatment services.
Keywords: cocaine use disorders; gender; posttraumatic stress disorder.
Conflict of interest statement
The authors report no conflicts of interest. The authors alone are responsible for the content and writing of this article.
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References
-
- Alterman AI, McDermott PA, Cook TG, Cacciola JS, McKay JR, McLellan AT, Rutherford MJ. Generalizability of the clinical dimensions of the Addiction Severity Index to nonopioid-dependent patients. Psychology of Addictive Behavaviors. 2000;14(3):287–294. - PubMed
-
- Back SE, Brady KT, Jaanimagi U, Jackson JL. Cocaine dependence and PTSD: A pilot study of symptom interplay and treatment preferences. Addictive Behaviors. 2006;31(2):351–354. - PubMed
-
- Back S, Dansky BS, Coffey SF, Saladin ME, Sonne S, Brady KT. Cocaine dependence with and without post-traumatic stress disorder: A comparison of substance use, trauma history and psychiatric comorbidity. American Journal on Addictions. 2000;9(1):51–62. - PubMed
-
- Blanchard EB, Jones-Alexander J, Buckley TC, Forneris CA. Psychometric properties of the PTSD Checklist (PCL) Behaviour Research and Therapy. 1996;34(8):669–673. - PubMed
-
- Brady KT, Dansky BS, Sonne SC, Saladin ME. Posttraumatic stress disorder and cocaine dependence: Order of onset. American Journal on Addictions. 1998;7(2):128–135. - PubMed
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