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Comment
. 2015 Mar;17(3):214-5.
doi: 10.1038/ncb3125.

Huntingtin facilitates selective autophagy

Amir Gelman  1 , Moran Rawet-Slobodkin  1 , Zvulun Elazar  1
Affiliations
Comment

Huntingtin facilitates selective autophagy

Amir Gelman et al. Nat Cell Biol. 2015 Mar.

Abstract

Selective autophagy is essential for maintaining cellular homeostasis under different growth conditions. Huntingtin, mutated versions of which have been implicated in Huntington disease, is now shown to act as a scaffold protein that couples the induction of autophagy and the selective recruitment of cargo into autophagosomes.

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References

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