Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2015 Jan-Jun;9(1):82-4.
doi: 10.4103/0973-6247.150959.

A case of Hepatitis E in a blood donor

Anita A Tendulkar  1 , Sneha A Shah  1 , Rohini A Kelkar  2
Affiliations
Case Reports

A case of Hepatitis E in a blood donor

Anita A Tendulkar et al. Asian J Transfus Sci. 2015 Jan-Jun.

Abstract

The threat of hepatitis E is being felt in blood banks in recent times. The disease is usually self-limiting, but may progress to a fulminant fatal form. We report a unique case of a hepatitis E virus (HEV)-positive asymptomatic blood donor who later developed jaundice and informed the blood bank. A blood donor passed all eligibility criteria tests and donated blood. After 20 days, the blood bank was informed by the donor that he had developed vomiting and jaundice 1 day postdonation. He was investigated by a local laboratory 1 day postdonation for liver profile, which was high. There had been a major outbreak in his community of similar symptoms during the same period. HEV IgM antibody by enzyme-linked immunosorbent assay was positive. Silent infections may be lurking in apparently healthy donors. Donors need to be encouraged to revert in case of any significant developments after donation and maintain open channels of communication.

Keywords: Blood donor; hepatitis E; screening.

PubMed Disclaimer

Conflict of interest statement

Conflicting Interest: None declared.

Figures

Figure 1
Figure 1
Geographic distribution of hepatitis E infection (2010) (Teo, Chong-Gee, Centres for Disease Control and Prevention, 2012 Yellow Book)
Figure 2
Figure 2
Schematic representation of hepatitis E virus infection: Typical serologic course (Centres for Disease Control and Prevention)
See this image and copyright information in PMC

References

    1. Bajpai M, Gupta E. Transfusion-transmitted hepatitis E: Is screening warranted? Indian J Med Microbiol. 2011;29:353–8. - PubMed
    1. Matsubayashi K, Kang JH, Sakata H, Takahashi K, Shindo M, Kato M, et al. A case of transfusion-transmitted hepatitis E caused by blood from a donor infected with hepatitis E virus via zoonotic food-borne route. Transfusion. 2008;48:1368–75. - PubMed
    1. Boxall E, Herborn A, Kochethu G, Pratt G, Adams D, Ijaz S, et al. Transfusion-transmitted hepatitis E in a ‘nonhyperendemic’ country. Transfus Med. 2006;16:79–83. - PubMed
    1. Colson P, Coze C, Gallian P, Henry M, De Micco P, Tamalet C. Transfusion-associated hepatitis E, France. Emerg Infect Dis. 2007;13:648–9. - PMC - PubMed
    1. Khuroo MS, Kamili S, Yattoo GN. Hepatitis E virus infection may be transmitted through blood transfusions in an endemic area. J GastroenterolHepatol. 2004;19:778–84. - PubMed

Publication types

LinkOut - more resources