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Case Reports
. 2015 Jan-Jun;9(1):89-91.
doi: 10.4103/0973-6247.150963.

Report of two cases of anti-M antibody in antenatal patients

Joseph Philip  1 , Neerja Kushwaha  1 , Neelesh Jain  1
Affiliations
Case Reports

Report of two cases of anti-M antibody in antenatal patients

Joseph Philip et al. Asian J Transfus Sci. 2015 Jan-Jun.

Abstract

Anti-M is a relatively common naturally occurring antibody reacting optimally at 4°C and weakly or nonreactive at 37°C. It is usually clinically insignificant but can be active at 37°C because of thermal amplitude of IgM component or presence of IgG component. It can cause or delayed hemolytic transfusion reactions or hemolytic disease of newborn. At our center we have encountered two cases of anti-M antibodies- one presenting as crossmatch incompatibility and other as blood grouping discrepancy in the last 8 months.

Keywords: Anti-M antibody; antenatal; hemolytic disease of fetus and newborn.

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Conflict of interest statement

Conflict of Interest: None declared.

Figures

Figure 1
Figure 1
LISS Coomb's gel card showing three-cell panel antibody screening results at 37°C
Figure 2
Figure 2
LISS Coomb's gel card showing one to 11-cell panel antibody identification results at 37°C
Figure 3
Figure 3
LISS Coomb's gel card showing three-cell panel antibody screening results at 37°C
Figure 4
Figure 4
NaCl gel card showing one to 11-cell panel antibody identification results at 4°C
See this image and copyright information in PMC

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