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Review
. 2014 Oct-Dec;7(4):189-97.
doi: 10.4103/0974-2077.150734.

Principles and Methods of Preparation of Platelet-Rich Plasma: A Review and Author's Perspective

Affiliations
Review

Principles and Methods of Preparation of Platelet-Rich Plasma: A Review and Author's Perspective

Rachita Dhurat et al. J Cutan Aesthet Surg. 2014 Oct-Dec.

Abstract

The utility of platelet-rich plasma (PRP) has spanned various fields of dermatology from chronic ulcer management to trichology and aesthetics, due to its role in wound healing. Though PRP is being used over a long time, there is still confusion over proper terminology to define, classify and describe the different variations of platelet concentrates. There is also a wide variation in the reported protocols for standardization and preparation of PRP, in addition to lack of accurate characterization of the tested products in most articles on the topic. Additionally, the high cost of commercially available PRP kits, precludes its use over a larger population. In this article, we review the principles and preparation methods of PRP based on available literature and place our perspective in standardizing a safe, simple protocol that can be followed to obtain an optimal consistent platelet yield.

Keywords: Platelet-rich plasma; preparation; principles; standardization.

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Conflict of interest statement

Conflict of Interest: None declared.

Figures

Figure 1
Figure 1
Flowchart describing preparation of PRP
Figure 2
Figure 2
Venipuncture using BD Eclipse™ blood collection needle
Figure 3
Figure 3
Consistency of PRP yield

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