Response to letter by Forike et al.: more rigorous, not less, external validation is needed

Affiliations

¹ Department of Cardiology, Bern University Hospital, Bern, Switzerland.
² Stanford Prevention Research Center, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Health Research and Policy, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Statistics, Stanford University School of Humanities and Sciences, 1265 Welch Rd., Stanford, CA 94305, USA. Electronic address: jioannid@stanford.edu.

Comment

George C M Siontis et al. J Clin Epidemiol. 2016 Jan.

. 2016 Jan:69:250-1.

doi: 10.1016/j.jclinepi.2015.01.021. Epub 2015 Jan 31.

¹ Department of Cardiology, Bern University Hospital, Bern, Switzerland.
² Stanford Prevention Research Center, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Health Research and Policy, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Statistics, Stanford University School of Humanities and Sciences, 1265 Welch Rd., Stanford, CA 94305, USA. Electronic address: jioannid@stanford.edu.

No abstract available

Comment on

External validation of new risk prediction models is infrequent and reveals worse prognostic discrimination.
Siontis GC, Tzoulaki I, Castaldi PJ, Ioannidis JP. Siontis GC, et al. J Clin Epidemiol. 2015 Jan;68(1):25-34. doi: 10.1016/j.jclinepi.2014.09.007. Epub 2014 Oct 23. J Clin Epidemiol. 2015. PMID: 25441703
External validation is only needed when prediction models are worth it (Letter commenting on: J Clin Epidemiol. 2015;68:25-34).
Martens FK, Kers JG, Janssens AC. Martens FK, et al. J Clin Epidemiol. 2016 Jan;69:249-50. doi: 10.1016/j.jclinepi.2015.01.022. Epub 2015 Feb 3. J Clin Epidemiol. 2016. PMID: 25726454 No abstract available.