Current therapies in hepatorenal syndrome
- PMID: 25726622
Current therapies in hepatorenal syndrome
Retraction in
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Retraction of six papers from Romanian Journal of Internal Medicine.Rom J Intern Med. 2016 Dec;54(4):256. doi: 10.1515/rjim-2016-0042. Epub 2016 Jul 15. Rom J Intern Med. 2016. PMID: 27428848 No abstract available.
Abstract
Hepatorenal syndrome (HRS) is a serious complication of liver cirrhosis with critically poor prognosis. The pathophysiologic hallmark is severe renal vasoconstriction, resulting from complex changes in splanchnic and general circulations as well as systemic and renal vasoconstrictors and vasodilators. Rapid diagnosis and management are important, since recent treatment modalities including vasoconstrictor therapy can improve short-term outcome and buy time for liver transplantation, which can result in complete recovery.