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. 1989 Nov 18;2(8673):1184-7.
doi: 10.1016/s0140-6736(89)91793-5.

HTLV-1 and polymyositis in Jamaica

O S Morgan  1 , P Rodgers-Johnson, C Mora, G Char
Affiliations

HTLV-1 and polymyositis in Jamaica

O S Morgan et al. Lancet. .

Abstract

IgG antibodies to human T-cell lymphotropic virus (HTLV-1) were found in 11 of 13 (85%) Jamaican patients with idiopathic adult polymyositis. The association was first observed in 7 patients with polymyositis who were included in a control group of 100 patients with neurological and neuromuscular diseases in a serological investigation of the prevalence of HTLV-1 antibody in patients with tropical spastic paraparesis. All 7 patients with polymyositis were positive for the antibody by an enzyme-linked immunosorbent assay, confirmed by western blot. Because of this striking association a further 6 patients with polymyositis were identified and tested, 4 of whom were also seropositive for HTLV-1 antibody.

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