Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2015 Feb 16:11:247-53.
doi: 10.2147/TCRM.S78124. eCollection 2015.

Reducing drug-herb interaction risk with a computerized reminder system

Affiliations

Reducing drug-herb interaction risk with a computerized reminder system

Sheng-Shing Lin et al. Ther Clin Risk Manag. .

Abstract

Background: Traditional Chinese medicine (TCM) and Western medicine are both popular in Taiwan. Approximately 14.1% of Taiwanese residents use Western drugs and Chinese herbs concurrently; therefore, drug-herb interaction is critical to patient safety. This paper presents a new procedure for reducing the risk of drug interactions.

Methods: Hospital computer systems are modified to ensure that drug-herb interactions are automatically detected when a TCM practitioner is writing a prescription. A pop-up reminder appears, warning of interactions, and the practitioner may adjust doses, delete herbs, or leave the prescription unchanged. A pharmacist will receive interaction information through the system and provide health education to the patient.

Results: During the 2011-2013 study period, 256 patients received 891 herbal prescriptions with potential drug-herb interactions. Three of the 50 patients who concurrently used ginseng and antidiabetic drugs manifested hypoglycemia (fasting blood sugar level ≤70 mg/dL).

Conclusion: Drug-herb interactions can cause adverse reactions. A computerized reminder system can enable TCM practitioners to reduce the risk of drug-herb interactions. In addition, health education for patients is crucial in avoiding adverse reaction by the interactions.

Keywords: Traditional Chinese medicine; Western medicine; adverse reaction.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Drug–herb interactions: from source articles to database.
Figure 2
Figure 2
Reminder system for drug–herb interactions.

References

    1. Chen FP, Chen TJ, Kung YY, et al. Use frequency of traditional Chinese medicine in Taiwan. BMC Health Serv Res. 2007;7:26. - PMC - PubMed
    1. Chen MC, Lai JN, Chen PC, Wang JD. Concurrent Use of Conventional Drugs with Chinese Herbal Products in Taiwan: A Population-based Study. J Tradit Complement Med. 2013;3(4):256–262. - PMC - PubMed
    1. Chan TY. Interaction between warfarin and danshen (Salvia miltiorrhiza) Ann Pharmacother. 2001;35(4):501–504. - PubMed
    1. Tsai HH, Lin HW, Lu YH, Chen YL, Mahady GB. A review of potential harmful interactions between anticoagulant/antiplatelet agents and Chinese herbal medicines. PloS One. 2013;8(5):e64255. - PMC - PubMed
    1. Liu Z, Li W, Li X, et al. Antidiabetic effects of malonyl ginsenosides from Panax ginseng on type 2 diabetic rats induced by high-fat diet and streptozotocin. J Ethnopharmacol. 2013;145(1):233–240. - PubMed