Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2015 Apr;11(4):200-1.
doi: 10.1038/nrrheum.2015.21. Epub 2015 Mar 3.

Musculoskeletal biology and bioengineering. A new in vivo stem cell model for regenerative rheumatology

Dennis McGonagle  1 , Elena A Jones  1
Affiliations
Comment

Musculoskeletal biology and bioengineering. A new in vivo stem cell model for regenerative rheumatology

Dennis McGonagle et al. Nat Rev Rheumatol. 2015 Apr.

Abstract

With advances in stem cell techniques for the bioengineering and regeneration of musculoskeletal tissues comes added complexity in our understanding of stem cell biology. How will the recent discovery of a novel stem cell subset, termed osteochondroreticular stem cells, contribute to progression in the field?

PubMed Disclaimer

Comment on

  • Gremlin 1 identifies a skeletal stem cell with bone, cartilage, and reticular stromal potential.
    Worthley DL, Churchill M, Compton JT, Tailor Y, Rao M, Si Y, Levin D, Schwartz MG, Uygur A, Hayakawa Y, Gross S, Renz BW, Setlik W, Martinez AN, Chen X, Nizami S, Lee HG, Kang HP, Caldwell JM, Asfaha S, Westphalen CB, Graham T, Jin G, Nagar K, Wang H, Kheirbek MA, Kolhe A, Carpenter J, Glaire M, Nair A, Renders S, Manieri N, Muthupalani S, Fox JG, Reichert M, Giraud AS, Schwabe RF, Pradere JP, Walton K, Prakash A, Gumucio D, Rustgi AK, Stappenbeck TS, Friedman RA, Gershon MD, Sims P, Grikscheit T, Lee FY, Karsenty G, Mukherjee S, Wang TC. Worthley DL, et al. Cell. 2015 Jan 15;160(1-2):269-84. doi: 10.1016/j.cell.2014.11.042. Cell. 2015. PMID: 25594183 Free PMC article.
  • Identification and specification of the mouse skeletal stem cell.
    Chan CK, Seo EY, Chen JY, Lo D, McArdle A, Sinha R, Tevlin R, Seita J, Vincent-Tompkins J, Wearda T, Lu WJ, Senarath-Yapa K, Chung MT, Marecic O, Tran M, Yan KS, Upton R, Walmsley GG, Lee AS, Sahoo D, Kuo CJ, Weissman IL, Longaker MT. Chan CK, et al. Cell. 2015 Jan 15;160(1-2):285-98. doi: 10.1016/j.cell.2014.12.002. Cell. 2015. PMID: 25594184 Free PMC article.

References

    1. Arthritis Rheum. 2003 May;48(5):1315-25 - PubMed
    1. Rheumatology (Oxford). 2008 Feb;47(2):126-31 - PubMed
    1. Nature. 2010 Aug 12;466(7308):829-34 - PubMed
    1. Cell Stem Cell. 2014 Aug 7;15(2):154-68 - PubMed
    1. Cell. 2015 Jan 15;160(1-2):285-98 - PubMed

Publication types

MeSH terms

Substances

LinkOut - more resources