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. 1989 Dec 1;8(12):3749-57.
doi: 10.1002/j.1460-2075.1989.tb08551.x.

Genetic and molecular mapping of the Hmt region of mouse

S Richards  1 , M Bucan, K Brorson, M C Kiefer, S W Hunt 3rd, H Lehrach, K F Lindahl
Affiliations

Genetic and molecular mapping of the Hmt region of mouse

S Richards et al. EMBO J. .

Abstract

We have mapped a new region of the mouse major histocompatibility complex (MHC) that contains the nuclear gene, Hmt, for the maternally transmitted antigen, Mta. The Hmt region of chromosome 17 lies between a recombinational breakpoint distal to Tla and another proximal to Tpx-1, thus including Pgk-2. A novel MHC class I gene fragment, R4B2, was cloned and mapped to this region as was another new class I gene, Thy19.4. Both lie proximal to Pgk-2, within the distal inversion in t-haplotypes. The presence of several other MHC class I genes in the Hmt region is predicted from analysis of the recombinants that define the region.

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References

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