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. 1989 Nov 25;2(8674):1261-3.
doi: 10.1016/s0140-6736(89)91862-x.

Drug companies' evidence to justify advertising

V A Wade  1 , P R Mansfield, P J McDonald
Affiliations

Drug companies' evidence to justify advertising

V A Wade et al. Lancet. .

Abstract

Ten international pharmaceutical companies were asked by letter to supply their best evidence in support of marketing claims for seventeen products. Fifteen replies were received. Seven replies cited a total of 67 references: 31 contained relevant original data and only 13 were controlled trials, all of which had serious methodological flaws. There were four reports of changes in advertising claims and one company ceased marketing nikethamide in the third world. Standards of evidence used to justify advertising claims are inadequate.

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  • Evening primrose oil and eczema.
    Sharpe GR, Farr PM. Sharpe GR, et al. Lancet. 1990 Mar 17;335(8690):667-8. doi: 10.1016/0140-6736(90)90459-i. Lancet. 1990. PMID: 1969047 Clinical Trial. No abstract available.

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