Helix-helix interactions: is the medium the message?
- PMID: 25738383
- DOI: 10.1016/j.str.2015.02.004
Helix-helix interactions: is the medium the message?
Abstract
In this issue of Structure, Zhang and colleagues compare the helix-helix interaction spaces of an extensive database of soluble and membrane proteins. Intriguingly, the resultant clusters show similar helix interaction geometries between the protein classes, differing in detail only by patterns of local interactions and inter-helical distances.
Copyright © 2015 Elsevier Ltd. All rights reserved.
Comment on
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The membrane- and soluble-protein helix-helix interactome: similar geometry via different interactions.Structure. 2015 Mar 3;23(3):527-541. doi: 10.1016/j.str.2015.01.009. Epub 2015 Feb 19. Structure. 2015. PMID: 25703378 Free PMC article.
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