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Review
. 1989 Dec;2(8678-8679):1500-2.
doi: 10.1016/s0140-6736(89)92941-3.

Use of cyclosporin in psoriasis

J D Bos  1 , M M Meinardi, T van Joost, F Heule, A V Powles, L Fry
Affiliations
Review

Use of cyclosporin in psoriasis

J D Bos et al. Lancet. 1989 Dec.

Abstract

In the treatment of severe psoriasis, cyclosporin may achieve improvement or remission at low doses, but relapse usually occurs on withdrawal of treatment. An initial dose of 3 mg/kg per day is recommended. Complete remission should not be the objective, and the role of long-term maintenance cyclosporin therapy is uncertain because of potential side-effects--especially nephrotoxicity, hypertension, and a predisposition to malignancy. Guidelines are proposed for the assessment of such treatment.

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Comment in

  • Cyclosporin monitoring in psoriasis.
    Feutren G, Friend D, Timonen P, Laburte C. Feutren G, et al. Lancet. 1990 Apr 7;335(8693):866-7. doi: 10.1016/0140-6736(90)90990-m. Lancet. 1990. PMID: 1969599 No abstract available.

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