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Case Reports
. 2015 Feb;53(1):105-8.
doi: 10.3347/kjp.2015.53.1.105. Epub 2015 Feb 27.

Four additional cases of Diphyllobothrium nihonkaiense infection confirmed by analysis of COX1 gene in Korea

Sang Hyun Park  1 , Hyeong Kyu Jeon  2 , Jin Bong Kim  1
Affiliations
Case Reports

Four additional cases of Diphyllobothrium nihonkaiense infection confirmed by analysis of COX1 gene in Korea

Sang Hyun Park et al. Korean J Parasitol. 2015 Feb.

Abstract

Most of the diphyllobothriid tapeworms isolated from human samples in the Republic of Korea (= Korea) have been identified as Diphyllobothrium nihonkaiense by genetic analysis. This paper reports confirmation of D. nihonkaiense infections in 4 additional human samples obtained between 1995 and 2014, which were analyzed at the Department of Parasitology, Hallym University College of Medicine, Korea. Analysis of the mitochondrial cytochrome c oxidase 1 (cox1) gene revealed a 98.5-99.5% similarity with a reference D. nihonkaiense sequence in GenBank. The present report adds 4 cases of D. nihonkaiense infections to the literature, indicating that the dominant diphyllobothriid tapeworm species in Korea is D. nihonkaiense but not D. latum.

Keywords: Diphyllobothrium latum; Diphyllobothrium nihonkaiense; cox1 gene.

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Conflict of interest statement

We declare that we have no conflict of interest related to this work.

Figures

Fig. 1.
Fig. 1.
Aligned partial nucleotide sequences of a region of the mitochondrial cytochrome c oxidase subunit 1 gene of the DNA of adult Diphyllobothrium species. The sequences corresponded to 919-1,120 bp (total 203 bps) of the partial mitochondrial cox1 gene.
Fig. 2.
Fig. 2.
Phylogenetic tree of Diphyllobothrium nihonkaiense and D. latum based on the partial cox1 sequences inferred from neighbor-joining (NJ) analyses. Numbers on branches indicate the bootstrap value based on 3,000 replicates. There were 203 base pairs corresponding to positions 919-1,122 bp of the cox1 gene.
See this image and copyright information in PMC

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