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Comment
. 2015 Mar 5;16(3):219-20.
doi: 10.1016/j.stem.2015.02.008.

Hostile takeover: glioma stem cells recruit TAMs to support tumor progression

Yu Shi  1 , Yi-fang Ping  1 , Xia Zhang  1 , Xiu-wu Bian  2
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Hostile takeover: glioma stem cells recruit TAMs to support tumor progression

Yu Shi et al. Cell Stem Cell. .
Free article

Abstract

The dynamic interaction between cancer cells and immune cells is a critical concern for developing effective tumor immunotherapies. In a recent issue of Nature Cell Biology, Zhou et al. (2015) report that glioma stem cells secrete Periostin (POSTN), which recruits tumor-associated macrophages (TAMs) and supports the tumor-promoting M2 subtype.

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