Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2015 Apr;18(4):493-5.
doi: 10.1038/nn.3970. Epub 2015 Mar 9.

Explicit memory creation during sleep demonstrates a causal role of place cells in navigation

Gaetan de Lavilléon  1 , Marie Masako Lacroix  1 , Laure Rondi-Reig  2 , Karim Benchenane  1
Affiliations

Explicit memory creation during sleep demonstrates a causal role of place cells in navigation

Gaetan de Lavilléon et al. Nat Neurosci. 2015 Apr.

Abstract

Hippocampal place cells assemblies are believed to support the cognitive map, and their reactivations during sleep are thought to be involved in spatial memory consolidation. By triggering intracranial rewarding stimulations by place cell spikes during sleep, we induced an explicit memory trace, leading to a goal-directed behavior toward the place field. This demonstrates that place cells' activity during sleep still conveys relevant spatial information and that this activity is functionally significant for navigation.

PubMed Disclaimer

Comment in

References

    1. Nature. 2006 Nov 2;444(7115):56-60 - PubMed
    1. Neuron. 2001 Oct 11;32(1):141-9 - PubMed
    1. Physiol Behav. 1970 Feb;5(2):227-31 - PubMed
    1. Front Integr Neurosci. 2009 Mar 09;3:4 - PubMed
    1. J Neurosci Methods. 2006 Sep 15;155(2):207-16 - PubMed

Publication types

LinkOut - more resources