[Advances in studies on biotransformation of ginsensides]
- PMID: 25751936
[Advances in studies on biotransformation of ginsensides]
Abstract
Ginseng saponins are a type of important active substances in the ginseng genus plants. They have notable pharmacological activities of antineoplastic, neuroprotective, and hepatoprotective activities, which have been drawn more attention to obtain minor ginsenosides by all kinds of methods. In this review, we discussed the latest progress for enrichment of minor ginsenosides by biological transformation of major ginsenosides. At the same time, we have a brief outlook of the research at bioconversion of ginseng saponins.
Similar articles
-
A literature update elucidating production of Panax ginsenosides with a special focus on strategies enriching the anti-neoplastic minor ginsenosides in ginseng preparations.Appl Microbiol Biotechnol. 2017 May;101(10):4009-4032. doi: 10.1007/s00253-017-8279-4. Epub 2017 Apr 14. Appl Microbiol Biotechnol. 2017. PMID: 28411325 Review.
-
[Advances in studies on metabolism and biotansformation of ginsenosides in vitro].Zhongguo Zhong Yao Za Zhi. 2011 Aug;36(15):2021-6. Zhongguo Zhong Yao Za Zhi. 2011. PMID: 22066432 Chinese.
-
Application of microorganisms in Panax ginseng: cultivation of plants, and biotransformation and bioactivity of key component ginsenosides.Arch Microbiol. 2024 Oct 16;206(11):433. doi: 10.1007/s00203-024-04144-8. Arch Microbiol. 2024. PMID: 39412649 Review.
-
Biotransformation of ginsenosides by hydrolyzing the sugar moieties of ginsenosides using microbial glycosidases.Appl Microbiol Biotechnol. 2010 Jun;87(1):9-19. doi: 10.1007/s00253-010-2567-6. Epub 2010 Apr 8. Appl Microbiol Biotechnol. 2010. PMID: 20376631 Review.
-
[Advances in the biosynthesis research of ginsenosides].Yao Xue Xue Bao. 2013 Feb;48(2):170-8. Yao Xue Xue Bao. 2013. PMID: 23672012 Review. Chinese.
Cited by
-
The promising therapeutic potentials of ginsenosides mediated through p38 MAPK signaling inhibition.Heliyon. 2021 Nov 12;7(11):e08354. doi: 10.1016/j.heliyon.2021.e08354. eCollection 2021 Nov. Heliyon. 2021. PMID: 34825082 Free PMC article. Review.
-
Ginsenosides: A Potential Neuroprotective Agent.Biomed Res Int. 2018 May 8;2018:8174345. doi: 10.1155/2018/8174345. eCollection 2018. Biomed Res Int. 2018. PMID: 29854792 Free PMC article. Review.
-
Ginseng extract and ginsenosides improve neurological function and promote antioxidant effects in rats with spinal cord injury: A meta-analysis and systematic review.J Ginseng Res. 2022 Jan;46(1):11-22. doi: 10.1016/j.jgr.2021.05.009. Epub 2021 Jun 18. J Ginseng Res. 2022. PMID: 35058723 Free PMC article. Review.
-
Study on Transformation of Ginsenosides in Different Methods.Biomed Res Int. 2017;2017:8601027. doi: 10.1155/2017/8601027. Epub 2017 Dec 14. Biomed Res Int. 2017. PMID: 29387726 Free PMC article. Review.