Review
[Research progress on pharmacology, pharmacokinetics and determination of ergosta-4,6,8 (14),22-tetraen-3-one]
[Article in
Chinese]
- PMID: 25751937
Item in Clipboard
Review
[Research progress on pharmacology, pharmacokinetics and determination of ergosta-4,6,8 (14),22-tetraen-3-one]
[Article in
Chinese]
Zhongguo Zhong Yao Za Zhi.
2014 Oct.
Abstract
Ergosta-4,6,8(14),22-tetraen-3-one (ergone) is one of main components in many medicinal fungi. Ergone has been reported to possess the activities of diuresis, cytotoxicity, antitumor, immunosuppression, as well as treatment of chronic kidney disease. According to reported literatures, an overview of spectroscopy characteristics, content determination, pharmacological activity and pharmacokinetics, etc. for ergone is presented in this review. Furthermore, the present review can provide a certain reference value for the further study and development of ergone.
Similar articles
-
Enhanced distribution and anti-tumor activity of ergosta-4,6,8(14),22-tetraen-3-one by polyethylene glycol liposomalization.J Nanosci Nanotechnol. 2013 Feb;13(2):1435-9. doi: 10.1166/jnn.2013.6009. J Nanosci Nanotechnol. 2013. PMID: 23646655
-
Ergosta-4,6,8(14),22-tetraen-3-one induces G2/M cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells.Biochim Biophys Acta. 2011 Apr;1810(4):384-90. doi: 10.1016/j.bbagen.2010.12.005. Epub 2011 Jan 15. Biochim Biophys Acta. 2011. PMID: 21241775
-
Rapid resolution liquid chromatography-mass spectrometry and high-performance liquid chromatography-fluorescence detection for metabolism and pharmacokinetic studies of ergosta-4,6,8(14),22-tetraen-3-one.Anal Chim Acta. 2010 Aug 24;675(2):199-206. doi: 10.1016/j.aca.2010.07.029. Epub 2010 Jul 27. Anal Chim Acta. 2010. PMID: 20800733
-
Traditional uses, phytochemistry, pharmacology, pharmacokinetics and quality control of Polyporus umbellatus (Pers.) Fries: a review.J Ethnopharmacol. 2013 Aug 26;149(1):35-48. doi: 10.1016/j.jep.2013.06.031. Epub 2013 Jun 26. J Ethnopharmacol. 2013. PMID: 23811047 Review.
-
[Research progress studies on pharmacology and pharmacokinetics of ligustilide].Zhongguo Zhong Yao Za Zhi. 2012 Nov;37(22):3350-3. Zhongguo Zhong Yao Za Zhi. 2012. PMID: 23373200 Review. Chinese.
Cited by
-
Structure and Biological Activity of Ergostane-Type Steroids from Fungi.Molecules. 2022 Mar 24;27(7):2103. doi: 10.3390/molecules27072103. Molecules. 2022. PMID: 35408501 Free PMC article. Review.
-
Targeting cancer initiating cells by promoting cell differentiation and restoring chemosensitivity via dual inactivation of STAT3 and src activity using an active component of antrodia cinnamomea mycelia.Oncotarget. 2016 Nov 8;7(45):73016-73031. doi: 10.18632/oncotarget.12194. Oncotarget. 2016. PMID: 27682875 Free PMC article.
-
Ergosterone ameliorates RRR-induced spleen deficiency by gut microbiota-gut metabolites and P38MAPK signaling pathway.Front Microbiol. 2025 Mar 5;16:1501068. doi: 10.3389/fmicb.2025.1501068. eCollection 2025. Front Microbiol. 2025. PMID: 40109979 Free PMC article.