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Comment
. 2015 Apr;6(4):235-7.
doi: 10.1007/s13238-015-0141-9.

Periostin: a potent chemotactic factor for recruiting tumor-associated macrophage

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Comment

Periostin: a potent chemotactic factor for recruiting tumor-associated macrophage

Tiantian Wu et al. Protein Cell. 2015 Apr.
No abstract available

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Figures

Figure 1
Figure 1
Glioma stem cells (GSCs) secrete periostin (POSTN) to recruit and educate macrophages in glioblastoma (GBM). Tumor-associated macrophages (TAMs) are enriched in the POSTN-abundant perivascular niche in GBMs. GSC-secreted POSTN acts as a chemoattractant to recruit and maintain monocyte-derived M2 TAMs from the peripheral blood to promote GBM growth

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