Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2014 Sep;4(3):257-63.
doi: 10.1016/j.jceh.2014.03.052. Epub 2014 Apr 13.

Mesenteric venous thrombosis

Bashar Hmoud  1 , Ashwani K Singal  2 , Patrick S Kamath  3
Affiliations
Review

Mesenteric venous thrombosis

Bashar Hmoud et al. J Clin Exp Hepatol. 2014 Sep.

Abstract

Mesenteric vein thrombosis is increasingly recognized as a cause of mesenteric ischemia. Acute thrombosis commonly presents with abdominal pain and chronic type with features of portal hypertension. Contrast enhanced CT scan of abdomen is quite accurate for diagnosing and differentiating two types of mesenteric venous thrombosis. Prothrombotic state, hematological malignancy, and local abdominal inflammatory conditions are common predisposing conditions. Over the last decade, JAK-2 (janus kinase 2) mutation has emerged as an accurate biomarker for diagnosis of myeloproliferative neoplasm, an important cause for mesenteric venous thrombosis. Anticoagulation is the treatment of choice for acute mesenteric venous thrombosis. Thrombolysis using systemic or transcatheter route is another option. Patients with peritoneal signs or refractory to initial measures require surgical exploration. Increasing recognition of mesenteric venous thrombosis and use of anticoagulation for treatment has resulted in reduction in the need for surgery with improvement in survival.

Keywords: JAK2, janus kinase 2; MVT, mesenteric venous thrombosis; PVT, portal vein thrombosis; TIPS, transjugular intrahepatic portosystemic shunt; mesenteric venous thrombosis; portal hypertension; thrombosis.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Algorithm for management of acute and chronic mesenteric venous thrombosis. MVT: Mesenteric venous thrombosis; EVL: Endoscopic variceal ligation; BB: Beta blockers; TIPS: Transjugular intrahepatic portosystemic shunt.
See this image and copyright information in PMC

References

    1. Grendell J.H., Ockner R.K. Mesenteric venous thrombosis. Gastroenterology. 1982;82:358–372. - PubMed
    1. Zhang J., Duan Z.Q., Song Q.B., Luo Y.W., Xin S.J., Zhang Q. Acute mesenteric venous thrombosis: a better outcome achieved through improved imaging techniques and a changed policy of clinical management. Eur J Vasc Endovasc Surg. 2004;28:329–334. - PubMed
    1. Harnik I.G., Brandt L.J. Mesenteric venous thrombosis. Vasc Med. 2010;15:407–418. - PubMed
    1. Singal A.K., Kamath P.S., Tefferi A. Mesenteric venous thrombosis. Mayo Clin Proc Mayo Clin. 2013;88:285–294. - PubMed
    1. Brunaud L., Antunes L., Collinet-Adler S. Acute mesenteric venous thrombosis: case for nonoperative management. J Vasc Surg. 2001;34:673–679. - PubMed