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Case Reports
. 2013 Jun;1(1):24-6.
doi: 10.1055/s-0033-1341418. Epub 2013 Mar 19.

Use of Mitomycin C for Refractory Esophageal Stricture following Tracheoesophageal Fistula Repair

Anna Lakoma  1 , Sara C Fallon  1 , Shawn Mathur  1 , Eugene S Kim  1
Affiliations
Case Reports

Use of Mitomycin C for Refractory Esophageal Stricture following Tracheoesophageal Fistula Repair

Anna Lakoma et al. European J Pediatr Surg Rep. 2013 Jun.

Abstract

Esophageal stricture is a well-described complication following tracheoesophageal fistula repair. Herein, we report two patients who had persistent esophageal strictures after several months of repeat balloon dilatations. Each patient was treated with a single application of topical mitomycin C in addition to esophageal dilatation, which resulted in complete resolution of the stricture.

Keywords: esophageal stricture; mitomycin C; tracheoesophageal fistula.

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Conflict of interest statement

Conflict of Interest None

Figures

Fig. 1
Fig. 1
(a) Esophagram of a tight stricture (white arrow) at the anastomosis in a 39-week-old infant girl, born with VACTERL syndrome. (b) Esophagram showing resolution (white arrow) of the esophageal stricture after balloon dilatation and treatment with mitomycin C.
Fig. 2
Fig. 2
Illustration of an endoscopic view of an esophageal stricture dilated by balloon and treated with a cottonoid soaked in mitomycin C. (Illustration by Scott Holmes, reprinted with permission from Baylor College of Medicine, Houston, Texas, United States.)
See this image and copyright information in PMC

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