Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2015;63(3):237-43.
doi: 10.1248/cpb.c14-00779.

Tirucallane-type triterpenoids from the fruit of Ficus carica and their cytotoxic activity

Lin Jing  1 , Yang-Mei Zhang, Jian-Guang Luo, Ling-Yi Kong
Affiliations
Free article

Tirucallane-type triterpenoids from the fruit of Ficus carica and their cytotoxic activity

Lin Jing et al. Chem Pharm Bull (Tokyo). 2015.
Free article

Abstract

Nine new tirucallane-type triterpenoids, ficutirucins A-I (1-9), were isolated from the fruit of Ficus carica. Their structures were established on the basis of spectroscopic data and chemical methods. All isolates were evaluated for their cytotoxic activities against three human cancer cell lines, MCF-7, HepG-2, and U2OS. Compounds 1-3, 6, 7, and 9 exhibited moderate cytotoxic activities with IC50 values of 11.67-45.61 µM against one or more of the three cancer cell lines.

PubMed Disclaimer

Publication types