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. 2015 Mar 7;21(9):2754-8.
doi: 10.3748/wjg.v21.i9.2754.

Radical gastrectomy with hepatoarterial catheter implantation for late-stage gastric cancer

Guo-Liang Yao  1 , Yong-Gang Fan  1 , Jing-Ming Zhai  1 , Bao-Sai Lu  1 , Kai-Long Liu  1
Affiliations

Radical gastrectomy with hepatoarterial catheter implantation for late-stage gastric cancer

Guo-Liang Yao et al. World J Gastroenterol. .

Abstract

Aim: To determine the optimal type of surgery for late-stage gastric cancer with hepatic metastases.

Methods: We retrospectively analyzed 49 gastrectomies for late-stage gastric cancer conducted in the First Hospital Affiliated to Henan University of Science and Technology between September 2003 and September 2010. All gastrectomy operations were divided into two groups: radical resection (gastrectomy and simultaneous resection of hepatic metastases, n = 31), and palliative resection (gastrectomy without hepatic resection, n = 18). All 49 patients had chemotherapy catheter implantation in the hepatic artery via the gastroduodenal artery. Postoperative complications and cumulative survival rates of the two groups were compared and analyzed.

Results: There was no significant difference in the number of perioperative complications between the radical and palliative resection groups (6 and 3 cases, respectively, P > 0.05). The incidence of long-term complications including ileus (3 in the radical resection and 2 in the palliative resection groups) and anastomosis (2 cases in each group) was not significantly different (P > 0.05). The cumulative survival rate was significantly lower in the palliative resection group (P < 0.05).

Conclusion: Radical gastrectomy with resection of hepatic metastases and hepatoarterial catheter implantation is the recommended surgery for late-stage gastric cancer patients with hepatic metastases.

Keywords: Cumulative survival curve; Gastric cancer; Hepatic metastases; Palliative gastrectomy; Radical gastrectomy.

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Figures

Figure 1
Figure 1
Cumulative survival rate for radical resection group (Group 1) and palliative resection group (Group 2). Significantly longer survival was observed for the radical resection group.
See this image and copyright information in PMC

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