. 2015 Mar;61(3):251.

Does ezetimibe modify clinical outcomes?

Affiliations

¹ Pharmacist completing his doctoral training at the University of British Columbia in Vancouver.
² Associate Professor of General Internal Medicine at the University of Calgary in Alberta.
³ Professor and Director of Evidence-Based Medicine in the Department of Family Medicine at the University of Alberta in Edmonton.

Ricky D Turgeon et al. Can Fam Physician. 2015 Mar.

. 2015 Mar;61(3):251.

¹ Pharmacist completing his doctoral training at the University of British Columbia in Vancouver.
² Associate Professor of General Internal Medicine at the University of Calgary in Alberta.
³ Professor and Director of Evidence-Based Medicine in the Department of Family Medicine at the University of Alberta in Edmonton.

No abstract available

References

1. Cannon CP, Giugliano RP, Blazing MA, Harrington RA, Peterson JL, Sisk CM, et al. Rationale and design of IMPROVE-IT (IMProved Reduction of Outcomes: Vytorin Efficacy International Trial): comparison of ezetimibe/simvastatin versus simvastatin monotherapy on cardiovascular outcomes in patients with acute coronary syndromes. Am Heart J. 2008;156:826–32. - PubMed
1. IMPROVE-IT [slide presentation] American Heart Association; 2014. Available from: www.my.americanheart.org/idc/groups/ahamah-public/@wcm/@sop/@scon/docume.... Accessed 2014 Dec 16.
1. O’Riordan M. IMPROVE-IT: ‘Modest’ benefit when adding ezetimibe to statins in post-ACS patients. Chicago, IL: Medscape; 2014.
1. Kastelein JJ, Akdim F, Stroes ES, Zwinderman AH, Bots ML, Stalenhoef AF, et al. Simvastatin with or without ezetimibe in familial hypercholesterolemia. N Engl J Med. 2008;358:1431–43. - PubMed
1. Kouvelos GN, Arnaoutoglou EM, Matsagkas MI, Kostara C, Gartzonika C, Bairaktari ET, et al. Effects of rosuvastatin with or without ezetimibe on clinical outcomes in patients undergoing elective vascular surgery: results of a pilot study. J Cardiovasc Pharmacol Ther. 2013;18:5–12. - PubMed