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Review
. 2015 Nov;240(11):1387-95.
doi: 10.1177/1535370215576313. Epub 2015 Mar 13.

Parkinson's disease and enhanced inflammatory response

Iva Stojkovska  1 , Brandon M Wagner  1 , Brad E Morrison  2
Affiliations
Review

Parkinson's disease and enhanced inflammatory response

Iva Stojkovska et al. Exp Biol Med (Maywood). 2015 Nov.

Abstract

Parkinson's disease (PD) is the first and second most prevalent motor and neurodegenerative disease, respectively. The clinical symptoms of PD result from a loss of midbrain dopaminergic (DA) neurons. However, the molecular cause of DA neuron loss remains elusive. Mounting evidence implicates enhanced inflammatory response in the development and progression of PD pathology. This review examines current research connecting PD and inflammatory response.

Keywords: Parkinson’s disease; disease models; inflammation; neuroinflammation.

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