Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2015 Jul;21(7):1155-66.
doi: 10.1016/j.bbmt.2015.03.002. Epub 2015 Mar 11.

Hematopoietic Stem Cell Transplantation for Multiple Myeloma: Guidelines from the American Society for Blood and Marrow Transplantation

Nina Shah  1 , Natalie Callander  2 , Siddhartha Ganguly  3 , Zartash Gul  4 , Mehdi Hamadani  5 , Luciano Costa  6 , Salyka Sengsayadeth  7 , Muneer Abidi  8 , Parameswaran Hari  5 , Mohamad Mohty  9 , Yi-Bin Chen  10 , John Koreth  11 , Heather Landau  12 , Hillard Lazarus  13 , Helen Leather  14 , Navneet Majhail  15 , Rajneesh Nath  16 , Keren Osman  17 , Miguel-Angel Perales  12 , Jeffrey Schriber  18 , Paul Shaughnessy  19 , David Vesole  20 , Ravi Vij  21 , John Wingard  22 , Sergio Giralt  12 , Bipin N Savani  7 ; American Society for Blood and Marrow Transplantation
Affiliations
Free article
Review

Hematopoietic Stem Cell Transplantation for Multiple Myeloma: Guidelines from the American Society for Blood and Marrow Transplantation

Nina Shah et al. Biol Blood Marrow Transplant. 2015 Jul.
Free article

Abstract

Therapeutic strategies for multiple myeloma (MM) have changed dramatically over the past decade. Thus, the role of hematopoietic stem cell transplantation (HCT) must be considered in the context of this evolution. In this evidence-based review, we have critically analyzed the data from the most recent clinical trials to better understand how to incorporate HCT and when HCT is indicated. We have provided our recommendations based on strength of evidence with the knowledge that ongoing clinical trials make this a dynamic field. Within this document, we discuss the decision to proceed with autologous HCT, factors to consider before proceeding to HCT, the role of tandem autologous HCT, post-HCT maintenance therapy, and the role of allogeneic HCT for patients with MM.

Keywords: Guidelines; Multiple myeloma; Recommendations; Transplantation.

PubMed Disclaimer

MeSH terms

Substances