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Comment
. 2015 Apr 7;112(14):E1693.
doi: 10.1073/pnas.1500911112. Epub 2015 Mar 13.

Loss of HtrA1-induced attenuation of TGF-β signaling in fibroblasts might not be the main mechanism of CARASIL pathogenesis

Ju Liu  1 , Fengyun Dong  2 , Josephine Hoh  3
Affiliations
Comment

Loss of HtrA1-induced attenuation of TGF-β signaling in fibroblasts might not be the main mechanism of CARASIL pathogenesis

Ju Liu et al. Proc Natl Acad Sci U S A. .
No abstract available

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Fig. 1.
Fig. 1.
Expression pattern of HtrA1 in small arteries. RT-PCR analysis of HtrA1 expression in LCM-captured (A) and primary-cultured (B) ECs, VSMCs, and FBs from human coronary small arteries. n = 3, **P < 0.01. (C) Immunoblots of HtrA1 and β-actin protein in primary-cultured cells. (D) Quantification of HtrA1 secretion from primary-cultured cells by ELISA. n = 3, **P < 0.01.
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References

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