Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2015 Aug;19(8):1783-90.
doi: 10.1007/s10995-015-1692-3.

Parental Age and Autism Spectrum Disorders Among New York City Children 0-36 Months of Age

Affiliations

Parental Age and Autism Spectrum Disorders Among New York City Children 0-36 Months of Age

Carol A Quinlan et al. Matern Child Health J. 2015 Aug.

Abstract

We examined trends in autism spectrum disorders (ASD) and the association of ASD with parental age among young New York City (NYC) children. Children born in NYC to resident mothers from 1994-2001 were identified through vital statistics records (N = 927,003). Records were linked to data from NYC Early Intervention (EI) Program through 2004. The independent parental age-specific odds of having an ASD before 36 months of age were estimated using multiple logistic regression controlling for risk factors. The increase in ASD attributable to changes in parental age at birth was examined. Births to mothers and fathers 35 years or older increased 14.9 and 11.5 %, respectively, between 1994 and 2001. ASD prevalence in EI increased significantly from 1 in 3,300 children born in 1994 to 1 in 233 children born in 2001. Children born to mothers ages 25-29, 30-34 and 35 or older had significantly greater odds of being diagnosed with ASD than children of mothers younger than 25 years (OR 1.5, 1.6, and 1.9, respectively). Children born to fathers ages 35 or older (OR 1.4) had greater odds of ASD than children of fathers younger than 25. The change in parental age accounted for only 2.7 % of the increase in ASD prevalence. Older paternal age and maternal age were independently associated with increased risk of ASD. However, while parental age at birth increased between the 1994 and 2001 birth cohorts in NYC, it did not explain the increase in number of ASD cases.

PubMed Disclaimer

References

    1. Science. 2007 Apr 20;316(5823):445-9 - PubMed
    1. Pediatrics. 2011 Jun;127(6):1043-51 - PubMed
    1. J Child Psychol Psychiatry. 2005 Sep;46(9):963-71 - PubMed
    1. Am J Epidemiol. 2009 Nov 1;170(9):1118-26 - PubMed
    1. Am J Public Health. 2009 Sep;99(9):1673-9 - PubMed