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. 1985 Jan;47(1):112-7.
doi: 10.1128/iai.47.1.112-117.1985.

Effect of phenethyl alcohol on Staphylococcus aureus alpha-lysin production

K Y Lee, T H Birkbeck

Effect of phenethyl alcohol on Staphylococcus aureus alpha-lysin production

K Y Lee et al. Infect Immun. 1985 Jan.

Abstract

Phenethyl alcohol, at the maximum concentration which did not inhibit growth (0.3% [vol/vol]), inhibited the production of alpha-lysin and exoproteases but not that of delta-lysin in Staphylococcus aureus Wood 46. The inhibition of alpha-lysin was reversible, and transient accumulation of cell-associated alpha-lysin occurred in the presence of PEA. A precursor of alpha-lysin ca. 3,000 daltons larger than extracellular alpha-lysin was immunologically detected in the sodium dodecyl sulfate extracts of membranes and whole cells of phenethyl alcohol-treated S. aureus cultures. Also, a degraded form of alpha-lysin was detected in membranes prepared from cells lysed by lysostaphin but not in membranes from cells lysed with an X-press.

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References

    1. Lipids. 1971 Aug;6(8):546-53 - PubMed
    1. J Bacteriol. 1972 Jan;109(1):162-8 - PubMed
    1. Antimicrob Agents Chemother. 1977 May;11(5):906-8 - PubMed
    1. Eur J Biochem. 1978 May 16;86(2):589-602 - PubMed
    1. J Med Microbiol. 1978 Aug;11(3):303-13 - PubMed

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