Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Randomized Controlled Trial
. 2015 Mar 17;10(3):e0118368.
doi: 10.1371/journal.pone.0118368. eCollection 2015.

A new approach to improving healthcare personnel influenza immunization programs: a randomized controlled trial

Affiliations
Randomized Controlled Trial

A new approach to improving healthcare personnel influenza immunization programs: a randomized controlled trial

Larry W Chambers et al. PLoS One. .

Abstract

Background: Healthcare personnel influenza immunization rates remain sub-optimal. Following multiple studies and expert consultations, the "Successful Influenza Immunization Programs for Healthcare Personnel: A Guide for Program Planners" was produced. This trial assessed the impact of the Guide with facilitation in improving healthcare personnel influenza immunization rates in Canadian healthcare organizations.

Methods: A sample of 26 healthcare organizations across six Canadian provinces (ON, MB, NS, BC, SK, NL) was randomized to Intervention (n=13) or Control groups (n=13). Baseline influenza immunization rates were obtained for 2008-2009; the study groups were followed over two subsequent influenza seasons. The Intervention group received the Guide, facilitation support through workshops for managers and ongoing support. The Control groups conducted programs as usual. The Groups were compared using their reported influenza healthcare personnel influenza immunization rates and scores from a program assessment questionnaire.

Findings: Twenty-six organizations agreed to participate. 35% (9/26) of sites were acute care hospitals, 19% (5/26) continuing care, long-term care organizations or nursing homes, and 46% (12/26) were mixed acute care hospitals and long-term care or regional health authorities. The median rate of influenza immunization among healthcare personnel for the Intervention group was 43%, 44%, and 51% at three points in time respectively, and in the

Control group: 62%, 57%, and 55% respectively. No significant differences were observed between the groups at the three points in time. However, there was a 7% increase in the median rates between the Baseline Year and Year Two in the Intervention group, and a 6% decrease in the CONTROL GROUP over the same time period, which was statistically significant (0.071 versus -0.058, p < 0.001).

Interpretation: This pragmatic randomized trial of the Guide with facilitation of its implementation improved healthcare personnel immunization rates, but these rates continued to be sub-optimal and below rates achievable in programs requiring personnel to be immunized.

Trial registration: ClinicalTrials.gov NCT01207518.

PubMed Disclaimer

Conflict of interest statement

Competing Interests: The authors have declared that no competing interests exist.

References

    1. Committee on Infectious Diseases, American Academy of Pediatrics. Policy statement—recommendation for mandatory influenza immunization of all health care personnel. Pediatrics. 2010; 126(4), 809–815. 10.1542/peds.2010-2376 - DOI - PubMed
    1. Schanzer DL, Tam TW, Langley JM, Winchester BT (2007) Influenza-attributable deaths, canada 1990–1999 Epidemiology and Infection. 2007; 135(7), 1109–1116. - PMC - PubMed
    1. Kwong JC, Crowcroft NS, Campitelli MA, Ratnasingham S, Daneman N, Deeks SL, et al. Ontario burden of infectious disease study (ONBOIDS): An OAHPP/ICES report. Available: http://www.publichealthontario.ca/en/eRepository/ONBoID_ICES_Report_ma18... Accessed 2015 January 26.
    1. Centers for Disease Control and Prevention (2010) Estimates of deaths associated with seasonal influenza—united states, 1976–2007. MMWR. 2010; 59(33), 1057–62. - PubMed
    1. Public Health Agency of Canada. Reported influenza hospitalizations and deaths in canada: 2009–10 to 2013–14. 2014; Available: http://www.phac-aspc.gc.ca/influenza/flu-stat-eng.php#fig Accessed 2014 March 28.

Publication types

MeSH terms

Associated data