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. 2015 Mar 19;372(12):1168-70.
doi: 10.1056/NEJMcibr1500292.

A new antibiotic and the evolution of resistance

Cesar A Arias, Barbara E Murray

A new antibiotic and the evolution of resistance

Cesar A Arias et al. N Engl J Med. .
No abstract available

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Figures

Figure 1
Figure 1. Two Methods of Culturing Microorganisms from Soil
The traditional search for antibiotic agents involves culturing soil directly onto culture medium (e.g., an agar plate), which detects an estimated 1% of organisms present. Ling and colleagues used an isolation chip (iChip). After dilutions of soil are inoculated so that approximately one bacterial cell goes into each agar-filled chamber, the device is placed back in the soil. Many more bacteria survive and grow in the iChip than do on a traditional agar plate and, once established, are more likely to grow in vitro.
See this image and copyright information in PMC

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