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. 1985;313(6001):369-74.
doi: 10.1038/313369a0.

Unique allelic restriction fragments of the human Ha-ras locus in leukocyte and tumour DNAs of cancer patients

T G Krontiris, N A DiMartino, M Colb, D R Parkinson

Unique allelic restriction fragments of the human Ha-ras locus in leukocyte and tumour DNAs of cancer patients

T G Krontiris et al. Nature. 1985.

Abstract

White blood cell DNA from cancer patients and DNA from tumours and tumour-derived cell lines frequently demonstrated allelic restriction fragments of the Harvey ras oncogene locus not found in the unaffected population. The presence of such unusual alleles may be linked to susceptibility to cancer.

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