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. 2015 Apr;9(4):1937-1939.
doi: 10.3892/ol.2015.2902. Epub 2015 Jan 27.

Primary renal angiosarcoma with progressive clinical course despite surgical and adjuvant treatment: A case report

Filiz Celebi  1 , Kezban Nur Pilanci  2 , Sezer Saglam  2 , Numan Cem Balci  1
Affiliations

Primary renal angiosarcoma with progressive clinical course despite surgical and adjuvant treatment: A case report

Filiz Celebi et al. Oncol Lett. 2015 Apr.

Abstract

Angiosarcoma is an extremely rare, high-grade malignancy, which accounts for <2% of all soft-tissue sarcomas. Cases of primary renal angiosarcoma represent 1% of these. Angiosarcomas involving the kidney usually originate from metastatic skin lesions or primary visceral lesions and most often occur in the sixth and seventh decades of life. The present study describes a case of primary renal angiosarcoma that presented as a large right-sided renal mass with symptoms of flank pain. Despite surgical removal of the tumor, recurrent disease with associated lung metastases was identified at the surgical site following adjuvant chemotherapy. The patient succumbed to the disease 13 months after the diagnosis.

Keywords: cluster of differentiation 31; cluster of differentiation 34; nephrectomy; renal angiosarcoma.

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Figures

Figure 1
Figure 1
Contrast-enhanced computed tomography revealing a centrally necrotized and hemorrhagic right-sided renal mass with heterogenous peripheral enhancement.
Figure 2
Figure 2
Contrast-enhanced three-dimensional magnetic resonance imaging in (A) coronal and (B) axial planes revealing a necrotic mass in the lower portion of the right kidney with no central enhancement.
Figure 3
Figure 3
Computed tomography image of the thorax revealing the presence of multiple pleuropulmonary metastatic nodules and pleural effusion.
See this image and copyright information in PMC

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