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Comment
. 2015;14(8):1131-2.
doi: 10.1080/15384101.2015.1022075.

A deut of mTORC1/2 for cell adhesion

Long Chen  1 , Chunxiao Liu, Shile Huang
Affiliations
Comment

A deut of mTORC1/2 for cell adhesion

Long Chen et al. Cell Cycle. 2015.
No abstract available

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Figures

Figure 1.
Figure 1.
Schematic diagram of mTOR signaling in cell adhesion. Both mTORC1 and mTORC2 participate in IGF-1-stimulted cell adhesion in cancer cells. mTORC1 regulates cell adhesion through S6K1 and 4E-BP1/eIF4E pathways, but mTORC2 mediates cell adhesion independently of Akt. PP242 (an mTORC1/2 kinase inhibitor) suppresses cell adhesion more potently than rapamycin (an allosteric mTORC1 inhibitor).
See this image and copyright information in PMC

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