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Editorial
. 2015 Mar 19;4(3):e001897.
doi: 10.1161/JAHA.115.001897.

Balancing the risks and benefits of long-term antiplatelet therapies for cardiovascular disease: clinical, research, and regulatory implications

Affiliations
Editorial

Balancing the risks and benefits of long-term antiplatelet therapies for cardiovascular disease: clinical, research, and regulatory implications

Joakim Alfredsson et al. J Am Heart Assoc. .
No abstract available

Keywords: Editorials; arteriosclerosis; platelets; prevention; thrombin.

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References

    1. Leger AJ, Covic L, Kuliopulos A. Protease‐activated receptors in cardiovascular diseases. Circulation. 2006; 114:1070-1077. - PubMed
    1. Tricoci P, Huang Z, Held C, Moliterno DJ, Armstrong PW, Van de Werf F, White HD, Aylward PE, Wallentin L, Chen E, Lokhnygina Y, Pei J, Leonardi S, Rorick TL, Kilian AM, Jennings LH, Ambrosio G, Bode C, Cequier A, Cornel JH, Diaz R, Erkan A, Huber K, Hudson MP, Jiang L, Jukema JW, Lewis BS, Lincoff AM, Montalescot G, Nicolau JC, Ogawa H, Pfisterer M, Prieto JC, Ruzyllo W, Sinnaeve PR, Storey RF, Valgimigli M, Whellan DJ, Widimsky P, Strony J, Harrington RA, Mahaffey KWInvestigators T. Thrombin‐receptor antagonist vorapaxar in acute coronary syndromes. N Engl J Med. 2012; 366:20-33. - PubMed
    1. Morrow DA, Braunwald E, Bonaca MP, Ameriso SF, Dalby AJ, Fish MP, Fox KA, Lipka LJ, Liu X, Nicolau JC, Ophuis AJ, Paolasso E, Scirica BM, Spinar J, Theroux P, Wiviott SD, Strony J, Murphy SACommittee TPTS, Investigators. Vorapaxar in the secondary prevention of atherothrombotic events. N Engl J Med. 2012; 366:1404-1413. - PubMed
    1. Magnani G, Bonaca MP, Braunwald E, Dalby AJ, Fox KAA, Murphy SA, Nicolau JC, Ophuis TO, Scirica BM, Spinar J, Theroux P, Morrow DA. Efficacy and safety of vorapaxar as approved for clinical use in the United States. J Am Heart Assoc. 2015; 4:e00150510.1161/JAHA.114.001505 - PMC - PubMed
    1. Scirica BM, Bonaca MP, Braunwald E, De Ferrari GM, Isaza D, Lewis BS, Mehrhof F, Merlini PA, Murphy SA, Sabatine MS, Tendera M, Van de Werf F, Wilcox R, Morrow DAInvestigators TRAP‐TSC. Vorapaxar for secondary prevention of thrombotic events for patients with previous myocardial infarction: a prespecified subgroup analysis of the TRA 2 P‐TIMI 50 trial. Lancet. 2012; 380:1317-1324. - PubMed