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Review
. 2015 May 5:95:76-95.
doi: 10.1016/j.ejmech.2015.03.029. Epub 2015 Mar 14.

Recent advances in the chemistry and biology of pyridopyrimidines

F Buron  1 , J Y Mérour  1 , M Akssira  2 , G Guillaumet  1 , S Routier  3
Affiliations
Review

Recent advances in the chemistry and biology of pyridopyrimidines

F Buron et al. Eur J Med Chem. .

Abstract

The interest in pyridopyrimidine cores for pharmaceutical products makes this scaffold a highly useful building block for organic chemistry. These derivatives have found applications in various areas of medicine such as anticancer, CNS, fungicidal, antiviral, anti-inflammatory, antimicrobial, and antibacterial therapies. This review mainly focuses on the progress achieved since 2004 in the chemistry and biological activity of pyridopyrimidines.

Keywords: Heterocycles; Pharmacological activities; Pyridopyrimidine; Synthesis.

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