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Review
. 2015 May 1;23(9):1895-922.
doi: 10.1016/j.bmc.2015.02.056. Epub 2015 Mar 6.

Synthetic approaches to the 2013 new drugs

Hong X Ding  1 , Carolyn A Leverett  2 , Robert E Kyne Jr  3 , Kevin K-C Liu  4 , Sarah J Fink  5 , Andrew C Flick  6 , Christopher J O'Donnell  7
Affiliations
Review

Synthetic approaches to the 2013 new drugs

Hong X Ding et al. Bioorg Med Chem. .

Abstract

New drugs introduced to the market every year represent privileged structures for particular biological targets. These new chemical entities (NCEs) provide insight into molecular recognition and also serve as leads for designing future new drugs. This annual review covers the synthesis of twenty-four NCEs that were approved for the first time in 2013 and two 2012 drugs which were not covered during the previous edition of this review.

Keywords: Medicine; New chemical entities; New drug molecules; Synthesis; Therapeutic agents.

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