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. 2015;16(4):475-81.
doi: 10.4142/jvs.2015.16.4.475.

Helicobacter apodemus sp. nov., a new Helicobacter species identified from the gastrointestinal tract of striped field mice in Korea

Woo Jin Jeon  1   2 , Hee-Jin Dong  3 , Jae Hoon Shin  1 , Il Yong Kim  1 , Hungwui Ho  3 , Seung Hyun Oh  4 , Young Min Yoon  5 , Yang-Kyu Choi  6 , Jun Gyo Suh  7 , Ki-Hoan Nam  8 , Hyoung-Chin Kim  8 , Seongbeom Cho  3 , Je Kyung Seong  1
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Helicobacter apodemus sp. nov., a new Helicobacter species identified from the gastrointestinal tract of striped field mice in Korea

Woo Jin Jeon et al. J Vet Sci. 2015.

Abstract

A novel Helicobacter species was identified from the gastrointestinal tract of the Korean striped field mouse (Apodemus agrarius). Biochemical testing, ultrastructure characterization, and 16S rRNA gene sequence analysis suggested that this bacterium represents a distinct taxon. The bacterium was positive for urease activity, susceptible to cephalothin and nalidixic acid, and weakly positive for oxidase and catalase activity. Electron microscopy revealed that the bacterium has spirally curved rod morphology with singular bipolar nonsheathed flagella. Genotypically, the isolated bacterial strains (YMRC 000215, YMRC 000216, and YMRC 000419) were most closely related to a reference strain of Helicobacter mesocricetorum (97.25%, 97.32%, and 97.03% 16S rRNA sequence similarities, respectively). The 16S rRNA sequences of these strains were deposited into GenBank under accession numbers AF284754, AY009129, and AY009130, respectively. We propose the name Helicobacter apodemus for this novel species.

Keywords: 16S rRNA; Apodemus agrarius; Helicobacter apodemus; striped field mouse.

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Conflict of interest statement

Conflict of Interest: There is no conflict of interest.

Figures

Fig. 1
Fig. 1. Transmission electron micrograph of a negatively stained Helicobacter sp. Nov. cell isolated from the cecum of Apodemus agrarius. (A) YMRC 000215. (B) YMRC 000215. Scale bars = 1 µm (A), or 0.2 µm (B).
Fig. 2
Fig. 2. Phylogenetic tree of strains isolated in this study and members of other genera generated using the neighbor-joining method.
See this image and copyright information in PMC

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