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. 1985 Feb;12(1):57-9.

Significance of antikeratin antibodies in rheumatoid arthritis

V J Hajiroussou, J Skingle, A P Gillett, M Webley
  • PMID: 2580092

Significance of antikeratin antibodies in rheumatoid arthritis

V J Hajiroussou et al. J Rheumatol. 1985 Feb.

Abstract

Antikeratin antibodies (AKA) were found in the sera of 59% (121/204) of patients with rheumatoid arthritis (RA). There was a significantly higher incidence of AKA (73%) in male patients compared with females (53%) and a correlation between AKA positivity and IgM rheumatoid factor was found. Antibody reactivity was positively associated with the presence of nodules, antinuclear antibody, C-reactive protein and disease severity. AKA would appear to have possible prognostic significance in patients with RA.

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