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. 2015:2015:783936.
doi: 10.1155/2015/783936. Epub 2015 Feb 24.

Subacute sclerosing panencephalitis in a child with recurrent febrile seizures

Ayşe Kartal  1 , Ayşegül Neşe Çıtak Kurt  2 , Tuğba Hirfanoğlu  2 , Kürşad Aydın  2 , Ayşe Serdaroğlu  2
Affiliations

Subacute sclerosing panencephalitis in a child with recurrent febrile seizures

Ayşe Kartal et al. Case Rep Pediatr. 2015.

Abstract

Subacute sclerosing panencephalitis (SSPE) is a devastating disease of the central nervous system (CNS) caused by persistent mutant measles virus infection. The diagnosis of SSPE is based on characteristic clinical and EEG findings and demonstration of elevated antibody titres against measles in cerebrospinal fluid. Subacute sclerosing panencephalitis can have atypical clinical features at the onset. Herein, we report an unusual case of subacute sclerosing panencephalitis in a child with recurrent febrile seizures. The disease progressed with an appearance of myoclonic jerks, periodic high amplitude generalized complexes on EEG, and elevated titers of measles antibodies in cerebrospinal fluid leading to the final diagnosis of subacute sclerosing panencephalitis.

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Figures

Figure 1
Figure 1
Scalp electroencephalogram showing disorganized slow background with generalized spike-wave discharges.
See this image and copyright information in PMC

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