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. 2015 Oct;27(7):1199-222.
doi: 10.1177/0898264315577590. Epub 2015 Mar 24.

A Summary Score for the Framingham Heart Study Neuropsychological Battery

Brian Downer  1 , David W Fardo  2 , Frederick A Schmitt  2
Affiliations

A Summary Score for the Framingham Heart Study Neuropsychological Battery

Brian Downer et al. J Aging Health. 2015 Oct.

Abstract

Objective: To calculate three summary scores of the Framingham Heart Study neuropsychological battery and determine which score best differentiates between subjects classified as having normal cognition, test-based impaired learning and memory, test-based multidomain impairment, and dementia.

Method: The final sample included 2,503 participants. Three summary scores were assessed: (a) composite score that provided equal weight to each subtest, (b) composite score that provided equal weight to each cognitive domain assessed by the neuropsychological battery, and (c) abbreviated score comprised of subtests for learning and memory. Receiver operating characteristic analysis was used to determine which summary score best differentiated between the four cognitive states.

Results: The summary score that provided equal weight to each subtest best differentiated between the four cognitive states.

Discussion: A summary score that provides equal weight to each subtest is an efficient way to utilize all of the cognitive data collected by a neuropsychological battery.

Keywords: cognition; dementia; mild cognitive impairment.

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Conflict of interest statement

Declaration of Conflicting Interests

The authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

Figure 1
Figure 1
ROC curves differentiating between cognitively normal and demented participants. Note. ROC = receiver operator characteristic.
Figure 2
Figure 2
ROC curves differentiating between cognitively normal and ILMTB participants. Note. ROC = receiver operator characteristic; ILMTB = test-based impaired learning and memory.
Figure 3
Figure 3
ROC curves differentiating between cognitively normal and MDITB participants. Note. ROC = receiver operator characteristic; MDITB = test-based multidomain impairment.
Figure 4
Figure 4
ROC curves differentiating between demented and ILMTB participants. Note. ROC = receiver operator characteristic; ILMTB = test-based impaired learning and memory.
Figure 5
Figure 5
ROC curves differentiating between demented and MDITB participants. Note. ROC = receiver operator characteristic; MDITB = test-based multidomain impairment.
Figure 6
Figure 6
ROC curves differentiating between ILMTB and MDITB participants. Note. ROC = receiver operator characteristic; ILMTB = test-based impaired learning and memory; MDITB = test-based multidomain impairment.
See this image and copyright information in PMC

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