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Comment
. 2015 Mar 23;32(6):657-8.
doi: 10.1016/j.devcel.2015.03.008.

Fatty acid metabolism meets organelle dynamics

Laurence Walch  1 , Alenka Čopič  1 , Catherine L Jackson  2
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Comment

Fatty acid metabolism meets organelle dynamics

Laurence Walch et al. Dev Cell. .
Free article

Abstract

Upon nutrient deprivation, cells metabolize fatty acids (FAs) in mitochondria to supply energy, but how FAs, stored as triacylglycerols in lipid droplets, reach mitochondria has been mysterious. Rambold et al. (2015) now show that FA mobilization depends on triacylglycerol lipolysis, whereas autophagy feeds the lipid droplet pool for continued fueling of mitochondria.

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