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Review
. 2015 Mar 9:6:38.
doi: 10.3389/fneur.2015.00038. eCollection 2015.

PET Imaging of Tau Pathology in Alzheimer's Disease and Tauopathies

Affiliations
Review

PET Imaging of Tau Pathology in Alzheimer's Disease and Tauopathies

Olga G James et al. Front Neurol. .
No abstract available

Keywords: Alzheimer’s disease; PET neuroimaging; dementia; tau pathologies; tau proteins.

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Figures

Figure 1
Figure 1
(A) Normal 18F-AV-1451 PET study illustrating a tau-PET scan from an elderly cognitively normal subject (MMSE score of 30). No abnormal uptake is demonstrated above diffuse background activity. (B) Abnormal 18F-AV-1451 PET study illustrating a tau-PET scan images of a subject with mild Alzheimer’s disease (MMSE score of 22). Unlike an individual with normal cognition, there is abnormally increased radiotracer uptake distributed in the temporal lobes bilaterally. Source: Duke University.

References

    1. Prince M, Bryce R, Albanese E, Wimo A, Ribeiro W, Ferri CP. The global prevalence of dementia: a systematic review and metaanalysis. Alzheimers Dement (2013) 9(1):63–75 e210.1016/j.jalz.2012.11.007 - DOI - PubMed
    1. Thies W, Bleiler L, Alzheimer’s A. 2013 Alzheimer’s disease facts and figures. Alzheimers Dement (2013) 9(2):208–4510.1016/j.jalz.2013.02.003 - DOI - PubMed
    1. Beach TG, Monsell SE, Phillips LE, Kukull W. Accuracy of the clinical diagnosis of Alzheimer disease at National Institute on Aging Alzheimer disease centers, 2005-2010. J Neuropathol Exp Neurol (2012) 71(4):266–7310.1097/NEN.0b013e31824b211b - DOI - PMC - PubMed
    1. Jellinger KA, Attems J. Challenges of multimorbidity of the aging brain: a critical update. J Neural Transm (2014).10.1007/s00702-014-1288-x - DOI - PubMed
    1. McKhann GM, Knopman DS, Chertkow H, Hyman BT, Jack CR, Jr, Kawas CH, et al. The diagnosis of dementia due to Alzheimer’s disease: recommendations from the National Institute on Aging-Alzheimer’s association workgroups on diagnostic guidelines for Alzheimer’s disease. Alzheimers Dement (2011) 7(3):263–910.1016/j.jalz.2011.03.005 - DOI - PMC - PubMed

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