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. 2015 Mar 19;5(1):120-35.
doi: 10.3390/membranes5010120.

Preparation and preliminary dialysis performance research of polyvinylidene fluoride hollow fiber membranes

Qinglei Zhang  1 , Xiaolong Lu  2   3 , Juanjuan Liu  4 , Lihua Zhao  5
Affiliations

Preparation and preliminary dialysis performance research of polyvinylidene fluoride hollow fiber membranes

Qinglei Zhang et al. Membranes (Basel). .

Abstract

In this study, the separation properties of Polyvinylidene fluoride (PVDF) hollow fiber hemodialysis membranes were improved by optimizing membrane morphology and structure. The results showed that the PVDF membrane had better mechanical and separation properties than Fresenius Polysulfone High-Flux (F60S) membrane. The PVDF membrane tensile stress at break, tensile elongation and bursting pressure were 11.3 MPa, 395% and 0.625 MPa, respectively. Ultrafiltration (UF) flux of pure water reached 108.2 L∙h-1∙m-2 and rejection of Albumin from bovine serum was 82.3%. The PVDF dialyzers were prepared by centrifugal casting. The influences of membrane area and simulate fluid flow rate on dialysis performance were investigated. The results showed that the clearance rate of urea and Lysozyme (LZM) were improved with increasing membrane area and fluid flow rate while the rejection of albumin from bovine serum (BSA) had little influence. The high-flux PVDF dialyzer UF coefficient reached 62.6 mL/h/mmHg. The PVDF dialyzer with membrane area 0.69 m2 has the highest clearance rate to LZM and urea. The clearance rate of LZM was 66.8% and urea was 87.7%.

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Figures

Figure 1
Figure 1
The apparatus for determining the Max pore size of the hollow fiber membranes [2] 1: nitrogen bottle; 2: regulator; 3: precise pressure gauge; 4: valve; 5: container; 6: syringe needles; 7: Transparent cylinder; 8: PVDF membrane sample to be tested; and 9: absolute ethyl alcohol.
Figure 2
Figure 2
The SEM morphologies of different PVDF membranes, the labels M-1, M-2, M-3 and M-4 are membranes with PEG molecular weights 2, 4, 6 and 10 kDa, respectively.
Figure 3
Figure 3
The max pore size of PVDF membranes with different PEG molecular weight
Figure 4
Figure 4
The SEM morphologies of different PVDF membranes, the labels M-14.8, M-16.8, M-3 and M-20.8 are membranes with PEG content 14.8, 16.8, 18.8 and 20.8 wt %.
Figure 4
Figure 4
The SEM morphologies of different PVDF membranes, the labels M-14.8, M-16.8, M-3 and M-20.8 are membranes with PEG content 14.8, 16.8, 18.8 and 20.8 wt %.
Figure 5
Figure 5
The max pore size of PVDF membranes with different PEG content.
Figure 6
Figure 6
The stress-strain curves of different PVDF membranes, the labels M-1, M-2, M-3 and M-4 are membranes with PEG molecular weights 2, 4, 6 and 10 kDa, respectively.
Figure 7
Figure 7
The stress-strain curves of different PVDF membranes; the labels M-14.8, M-16.8, M-3, and M-20.8 are membranes with PEG content: 14.8, 16.8, 18.8 and 20.8 wt %, respectively.
Figure 8
Figure 8
The PVDF and F60S membranes SEM morphologies; M-0 is the PVDF membrane that was prepared in a previous study [2].
Figure 9
Figure 9
The PVDF and F60S membranes stress-strain curve, M-0 is the PVDF membrane that was prepared in a previous study [2].
Figure 10
Figure 10
The UF coefficient of PVDF dialyzer.
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