Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2015 Mar:32:118-23.
doi: 10.1016/j.ijid.2015.01.006.

Fluoroquinolone-resistant tuberculosis: implications in settings with weak healthcare systems

Kauser Jabeen  1 , Sadia Shakoor  1 , Rumina Hasan  2
Affiliations
Free article

Fluoroquinolone-resistant tuberculosis: implications in settings with weak healthcare systems

Kauser Jabeen et al. Int J Infect Dis. 2015 Mar.
Free article

Abstract

Fluoroquinolones (FQ) play an essential role in the treatment and control of multidrug-resistant tuberculosis (MDR-TB). They are also being evaluated as part of newer regimens under development for drug-sensitive TB. As newer FQ-based regimens are explored, knowledge of FQ resistance data from high TB burden countries becomes essential. We examine available FQ resistance data from high TB burden countries and demonstrate the need for comprehensive surveys to evaluate FQ resistance in these countries. The factors driving FQ resistance in such conditions and the cost of such resistance to weak healthcare systems are discussed. The need for a comprehensive policy for addressing the issue of FQ resistance is highlighted.

Keywords: Drug-resistant tuberculosis; Fluoroquinolone resistance; Health systems; Tuberculosis.

PubMed Disclaimer

MeSH terms