Effects of pure interferons on Epstein-Barr virus infection in vitro
- PMID: 2580994
- PMCID: PMC254835
- DOI: 10.1128/JVI.54.2.615-618.1985
Effects of pure interferons on Epstein-Barr virus infection in vitro
Abstract
Pure human gamma-interferon as well as alpha-interferon inhibited induction of immunoglobulin synthesis by Epstein-Barr virus but not by pokeweed mitogen in B lymphocytes from adult but not from newborn humans. The interferons inhibited the infected B lymphocytes directly, irrespective of the Epstein-Barr virus immune status of the donor, and their inhibitory effect was synergistic.
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